Advances in paediatric critical care have resulted in a reduction in mortality. This has shifted the focus to paediatric intensive care unit (PICU)-related morbidities and how to reduce or prevent them. In this study, we aimed to study the impact of paediatric intensive care unit (PICU) admission on neurocognitive performance. Intelligence quotient (IQ) was tested in 50 children (27 boys, 23 girls; mean age 6.98 years) 3 months after PICU discharge and in 75 controls using the Stanford-Binet IQ test. There was no statistically significant difference between patients and controls with regard to IQ scores, and no difference between medical and surgical patients (p > 0.05). IQ was unaffected by sedation, blood transfusion, or blood product transfusion. Patients who underwent a major surgical procedure, needed inotropic support, and needed mechanical ventilation had non-significantly lower IQ scores than those who did not. A non-significant negative correlation was observed between the length of PICU stay, mechanical ventilation duration, sedative use, and inotropic support. PICU admission does not appear to significantly affect cognitive outcomes in paediatric survivors.

中文翻译：

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儿科重症监护病房入院对儿童神经认知功能的影响

儿科重症监护的进步导致死亡率降低。这已将重点转移到儿科重症监护病房 (PICU) 相关的发病率以及如何减少或预防它们。在这项研究中，我们旨在研究儿科重症监护病房 (PICU) 入院对神经认知能力的影响。在 PICU 出院 3 个月后，对 50 名儿童（27 名男孩，23 名女孩；平均年龄 6.98 岁）和 75 名对照者使用 Stanford-Binet IQ 测试进行了智商 (IQ) 测试。患者和对照组的智商评分差异无统计学意义，内科患者和外科患者之间无统计学差异（p > 0.05）。智商不受镇静剂、输血或输血制品的影响。接受过大手术的患者，需要正性肌力支持，并且需要机械通气的人的智商分数比没有的人低。在 PICU 住院时间、机械通气时间、镇静剂使用和正性肌力支持之间观察到不显着的负相关。PICU 入院似乎不会显着影响儿科幸存者的认知结果。