Effects of long-term PM2.5 exposure on metabolic syndrome among adults and elderly in Guangdong, China,Environmental Health

当前位置： X-MOL 学术 › Environ. Health-Glob. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Effects of long-term PM2.5 exposure on metabolic syndrome among adults and elderly in Guangdong, China
Environmental Health ( IF 5.3 ) Pub Date : 2022-09-10 , DOI: 10.1186/s12940-022-00888-2
Xue-Yan Zheng ₁ , Si-Li Tang ₂ , Tao Liu ₃ , Ye Wang ₁ , Xiao-Jun Xu ₁ , Ni Xiao ₁ , Chuan Li ₁ , Yan-Jun Xu ₁ , Zhao-Xuan He ₁ , Shu-Li Ma ₄ , Yu-Liang Chen ₄ , Rui-Lin Meng ₁ , Li-Feng Lin _{1,

2}

Affiliation

We aimed to explore the association between long-term exposure to particulate matter ≤ 2.5 µm (PM2.5) and metabolic syndrome (MetS) and its components including fasting blood glucose (FBG), blood pressure, triglyceride (TG), high-density lipoprotein cholesterol (HDL-c) and waist circumference among adults and elderly in south China. We surveyed 6628 participants in the chronic disease and risk factors surveillance conducted in 14 districts of Guangdong province in 2015. MetS was defined based on the recommendation by the Joint Interim Societies’ criteria. We used the spatiotemporal land-use regression (LUR) model to estimate the two-year average exposure of ambient air pollutants (PM2.5, PM10, SO2, NO2, and O3) at individual levels. We recorded other covariates by using a structured questionnaire. Generalized linear mixed model was used for analysis. A 10-μg/m3 increase in the two-year mean PM2.5 exposure was associated with a higher risk of developing MetS [odd ratio (OR): 1.17, 95% confidence interval (CI): 1.01, 1.35], increased risk of fasting blood glucose level. (OR: 1.18, 95% CI: 1.02, 1.36), and hypertriglyceridemia (OR: 1.36, 95% CI: 1.18, 1.58) in the adjusted/unadjusted models (all P < 0.05). We found significant interaction between PM2.5 and the region, exercise on the high TG levels, and an interaction with the region, age, exercise and grain consumption on FBG (P interaction < 0.05). Long-term exposure to PM2.5 was associated with MetS, dyslipidemia and FBG impairment. Efforts should be made for environment improvement to reduce the burden of MetS-associated non-communicable disease.

更新日期：2022-09-11

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11