Study Objective

To evaluate continuance rates, bleeding patterns, and patient satisfaction with 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) use in adolescents and young adult women during the first 3 years of use

Design

We conducted an observational prospective study.

Setting

Family Planning Service of a tertiary hospital in Brazil

Participants

One hundred adolescents and young women aged 16-24 years.

Intervention

Insertion of 52-mg LNG-IUS for the main purpose of contraception. Follow-up visits were conducted at 12, 24, and 36 months after insertion.

Main Outcome Measures

Continuance rates, reasons for discontinuation of the method, and women's satisfaction and bleeding patterns

Results

Among those who were not lost to follow-up, LNG-IUS continuance rates were 89.1% (82/92), 82.9% (72/87), and 75.3% (64/85) in the first, second, and third years of use, respectively. The main reason for discontinuation was acne, followed by expulsion of/malpositioned LNG-IUS. Other reasons for discontinuation were irregular uterine bleeding, dysmenorrhea, and abdominal pain. The amenorrhea rates were 50%, 54.1%, and 39% at 12, 24, and 36 months, respectively. Spotting rates increased during the first 3 years of use (20.8%, 16.7%, and 26.6%, respectively). Adolescents and young women using the LNG-IUS showed high rates of satisfaction, with 93.9%, 100%, and 96.8% of women being very satisfied/satisfied in the first 3 years of use. Only 2 participants who continued using the LNG-IUS reported being very dissatisfied/dissatisfied in the third year of follow-up.

Conclusion

The LNG-IUS showed high rates of continuation and satisfaction in the first 3 years of use in Brazilian adolescents and young adults. Most women reported a favorable bleeding pattern.

中文翻译：

---

在青少年和年轻成年女性中使用 52 毫克左炔诺孕酮宫内缓释系统：3 年随访

学习目标

评估在青少年和年轻成年女性使用 52 mg 左炔诺孕酮宫内缓释系统 (LNG-IUS) 的前 3 年持续率、出血模式和患者满意度

设计

我们进行了一项观察性前瞻性研究。

环境

巴西某三级医院计划生育服务

参加者

一百名 16-24 岁的青少年和年轻女性。

干涉

以避孕为主要目的插入 52 毫克 LNG-IUS。在插入后 12、24 和 36 个月进行了随访。

主要观察指标

继续率、停止该方法的原因以及女性的满意度和出血模式

结果

在未失访的患者中，LNG-IUS 持续率在第一年、第二年和第三年分别为 89.1%（82/92）、82.9%（72/87）和 75.3%（64/85）分别使用。停药的主要原因是痤疮，其次是 LNG-IUS 排出/错位。其他停药原因包括不规则子宫出血、痛经和腹痛。12、24 和 36 个月的闭经率分别为 50%、54.1% 和 39%。在使用的前 3 年内，斑点率有所增加（分别为 20.8%、16.7% 和 26.6%）。使用 LNG-IUS 的青少年和年轻女性表现出很高的满意度，93.9%、100% 和 96.8% 的女性在使用的头 3 年内非常满意/满意。

结论

LNG-IUS 在巴西青少年和年轻人使用的前 3 年中显示出很高的持续率和满意度。大多数女性报告了良好的出血模式。