The search for more effective and selective metal-based anticancer drugs with fewer side effects has been an area of continuous exploration. This has led to the exploration of a wide range of metals from the periodic table, mainly from the d-block, as well as a wide variety of organic ligands, preferably with proven biological activity. Herein we review d-block transition metal complexes including tridentate Schiff bases from salicylaldehyde (O N O and O N N) that exhibit good results in preliminary anticancer and antitumor activity assays.

中文翻译：

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水杨醛衍生的三齿席夫碱（O N O 和 O N N）过渡金属络合物：其潜在抗癌活性分析

寻找更有效、选择性更强且副作用更少的金属抗癌药物一直是一个不断探索的领域。这导致人们对元素周期表中的各种金属（主要来自 d区）以及各种有机配体（最好具有经过验证的生物活性）进行了探索。在此，我们回顾了d区过渡金属配合物，包括来自水杨醛的三齿席夫碱（O N O 和 O N N），它们在初步抗癌和抗肿瘤活性测定中表现出良好的结果。