Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability.,Bone & Joint Research

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Exosomes from dysfunctional chondrocytes affect osteoarthritis in Sprague-Dawley rats through FTO-dependent regulation of PIK3R5 mRNA stability.
Bone & Joint Research ( IF 4.7 ) Pub Date : 2022-9-7 , DOI: 10.1302/2046-3758.119.bjr-2021-0443.r2
Guohua Lv ₁ , Bing Wang ₁ , Lei Li ₁ , Yunchao Li ₁ , Xinyi Li ₁ , Haoyu He ₁ , Lei Kuang ₁

Affiliation

Exosomes (exo) are involved in the progression of osteoarthritis (OA). This study aimed to investigate the function of dysfunctional chondrocyte-derived exo (DC-exo) on OA in rats and rat macrophages.

中文翻译：

来自功能失调的软骨细胞的外泌体通过 FTO 依赖性调节 PIK3R5 mRNA 稳定性影响 Sprague-Dawley 大鼠的骨关节炎。

外泌体 (exo) 参与骨关节炎 (OA) 的进展。本研究旨在探讨功能失调的软骨细胞衍生的 exo (DC-exo) 对大鼠和大鼠巨噬细胞 OA 的作用。

更新日期：2022-09-07

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