Coronavirus disease 2019 (COVID-19) is an important cause of morbidity in children in the United States (U.S.). Moreover, the U.S. has witnessed significant disparities affecting American Indian/Alaska Native, Black, and Hispanic/Latino children, stemming from systemic racism and social-structural inequalities and not differences in innate biological susceptibility. We review what is known on COVID-19 and health disparities in disease burden, access to care, pharmaceutical interventions, and clinical research in children, with a focus on the U.S. context. In addition, we propose strategies to communicate scientific data in ways that do not promote racism and biological susceptibility themes, and to address pediatric disparities in clinical infectious diseases research.

中文翻译：

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美国 COVID-19 儿童的种族、民族和健康差异：证据回顾和对未来的建议。

2019 年冠状病毒病 (COVID-19) 是美国 (US) 儿童发病的重要原因。此外，美国见证了影响美洲印第安人/阿拉斯加原住民、黑人和西班牙裔/拉丁裔儿童的显着差异，这些差异源于系统性种族主义和社会结构不平等，而不是先天生物易感性的差异。我们回顾了 COVID-19 的已知情况以及疾病负担、获得护理、药物干预和儿童临床研究方面的健康差异，重点是美国背景。此外，我们提出了以不促进种族主义和生物易感性主题的方式交流科学数据的策略，并解决了临床传染病研究中的儿科差异问题。