Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization,Journal of Cachexia, Sarcopenia and Muscle

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Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization
Journal of Cachexia, Sarcopenia and Muscle ( IF 9.4 ) Pub Date : 2022-09-04 , DOI: 10.1002/jcsm.13075
Natalie F Shur _{1,

2} , Elizabeth J Simpson _{2,

3} , Hannah Crossland _{2,

3} , Prince K Chivaka ₁ , Despina Constantin _{2,

3} , Sally M Cordon ₃ , Dumitru Constantin-Teodosiu ₃ , Francis B Stephens ₄ , Dileep N Lobo _{2,

3} , Nate Szewczyk _{2,

3,

5} , Marco Narici _{3,

6} , Clara Prats ₇ , Ian A Macdonald _{2,

3} , Paul L Greenhaff _{1,

2,

3}

Affiliation

Bed rest (BR) reduces whole-body insulin-stimulated glucose disposal (GD) and alters muscle fuel metabolism, but little is known about metabolic adaptation from acute to chronic BR nor the mechanisms involved, particularly when volunteers are maintained in energy balance.

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