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UBE2C mediated radiotherapy resistance of head and neck squamous cell carcinoma by regulating oxidative-stress-relative apoptosis
Aging-US ( IF 3.9 ) Pub Date : 2022-09-05 , DOI: 10.18632/aging.204265
Yingchun Zhou 1, 2 , Junbin Zhang 1, 2 , Jinglin Gong 1, 2 , Xi Tang 1, 2 , Chengyao Zhang 1, 2
Affiliation  

Purpose: Radiotherapy resistance is the main obstacle in the effective treatment of advanced head and neck squamous cell carcinoma (HNSCC). Increasing scientific opinions present that ubiquitin-conjugating enzyme E2C (UBE2C) might be a target gene acting as an oncogene.

中文翻译:

UBE2C通过调节氧化应激相关细胞凋亡介导头颈部鳞状细胞癌放疗抵抗

目的:放疗耐药是晚期头颈部鳞状细胞癌(HNSCC)有效治疗的主要障碍。越来越多的科学观点表明,泛素结合酶 E2C (UBE2C) 可能是作为致癌基因的靶基因。
更新日期:2022-09-05
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