Plasma Level of ATPase Inhibitory Factor 1 (IF1) and intrinsic capacity in community-dwelling older adults: Prospective data from the MAPT Study,medRxiv - Geriatric Medicine

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Plasma Level of ATPase Inhibitory Factor 1 (IF1) and intrinsic capacity in community-dwelling older adults: Prospective data from the MAPT Study
medRxiv - Geriatric Medicine Pub Date : 2022-09-02 , DOI: 10.1101/2022.09.02.22279534
Jaqueline Aragoni da Silva , Laurent O. Martinez , Yves Rolland , Souad Najib , Mikaël Croyal , Bertrand Perret , Nabila Jabrane-Ferrat , Hicham El Costa , Sophie Guyonnet , Bruno Vellas , Philipe de Souto Barreto ,

Background Intrinsic capacity (IC) is a function-related concept that reflects healthy aging. Identifying IC biomarkers is an essential step to slow down functional declines at early stages. ATPase inhibitory factor 1 (IF1) is a multifaceted protein that regulates mitochondrial oxidative phosphorylation (OXPHOS), thereby affecting cellular energy production.

中文翻译：

社区老年人 ATP 酶抑制因子 1 (IF1) 的血浆水平和内在能力：来自 MAPT 研究的前瞻性数据

背景内在能力 (IC) 是反映健康老龄化的功能相关概念。识别 IC 生物标志物是减缓早期功能衰退的重要步骤。ATPase 抑制因子 1 (IF1) 是一种多方面的蛋白质，可调节线粒体氧化磷酸化 (OXPHOS)，从而影响细胞能量的产生。

更新日期：2022-09-05

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