Arsenic is a highly active neuromodulator which can induce neurological disorders in invertebrates. The present study is a neurotoxicological approach to assess the toxicity of arsenic trioxide, where grooming behaviour is considered as a behavioural biomarker of arsenic induced stress in the prawns. Non-lethal exposure to arsenic trioxide, manipulates the expression pattern of neuroregulatory marker genes in a freshwater prawn, Macrobrachium lamarrei and induces symptoms of autism spectrum disorders (ASDs) in a short time.

中文翻译：

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砷诱导的鲢鱼神经调节基因表达的改变：梳理行为的神经毒理学方法

砷是一种高度活跃的神经调节剂，可在无脊椎动物中诱发神经系统疾病。本研究是一种评估三氧化二砷毒性的神经毒理学方法，其中梳理行为被认为是对虾砷诱导应激的行为生物标志物。非致命性的三氧化二砷暴露可操纵淡水虾、Macrobrachium lamarrei中神经调节标记基因的表达模式，并在短时间内诱发自闭症谱系障碍 (ASD) 的症状。