ort clinical management. In patients who have failed PONV prophylaxis, administering a rescue antiemetic from the same drug class has been reported to be ineffective. For many antiemetics currently used in PONV rescue, significant uncertainty remains around the effective dose range, speed of onset, duration of effect, safety, and overall risk-benefit ratio. As prompt, effective PONV rescue after failure of prophylaxis is important to optimize postoperative recovery and resource utilization, we conduct this systematic review to summarize the current evidence available on the topic....

中文翻译：

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术后恶心和呕吐的抢救治疗：对当前临床证据的系统评价

或临床管理。据报道，在 PONV 预防失败的患者中，使用相同药物类别的救援止吐剂是无效的。对于目前用于 PONV 抢救的许多止吐药，在有效剂量范围、起效速度、作用持续时间、安全性和总体风险收益比方面仍存在很大的不确定性。由于预防失败后及时、有效的 PONV 抢救对于优化术后恢复和资源利用很重要，我们进行了这项系统评价，以总结目前关于该主题的可用证据......