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Deep Brain Stimulation for Pediatric Dystonia: A Review of the Literature and Suggested Programming Algorithm
Journal of Child Neurology ( IF 2.0 ) Pub Date : 2022-09-02 , DOI: 10.1177/08830738221115248
Rose Gelineau-Morel 1 , Michael C. Kruer 2 , Jordan F. Garris 3 , Amal Abu Libdeh 3 , Daniel A. N. Barbosa 4 , Keith A. Coffman 1 , David Moon 5 , Christopher Barton 6, 7 , Alonso Zea Vera 8 , Adrienne B. Bruce 9, 10 , Travis Larsh 11, 12 , Steve W. Wu 11, 12 , Donald L. Gilbert 11, 12 , Jennifer A. O’Malley 13
Affiliation  

Deep brain stimulation (DBS) is an established intervention for use in pediatric movement disorders, especially dystonia. Although multiple publications have provided guidelines for deep brain stimulation patient selection and programming in adults, there are no evidence-based or consensus statements published for pediatrics. The result is lack of standardized care and underutilization of this effective treatment. To this end, we assembled a focus group of 13 pediatric movement disorder specialists and 1 neurosurgeon experienced in pediatric deep brain stimulation to review recent literature and current practices and propose a standardized approach to candidate selection, implantation target site selection, and programming algorithms. For pediatric dystonia, we provide algorithms for (1) programming for initial session and follow-up sessions, and (2) troubleshooting side effects encountered during programming. We discuss common side effects, how they present, and recommendations for management. This topical review serves as a resource for movement disorders specialists interested in using deep brain stimulation for pediatric dystonia.



中文翻译:

小儿肌张力障碍的深部脑刺激:文献回顾和建议的编程算法

深部脑刺激 (DBS) 是一种既定的干预措施,用于治疗儿科运动障碍,尤其是肌张力障碍。尽管多篇出版物为成人深部脑刺激患者的选择和编程提供了指南,但没有针对儿科发表的基于证据或共识的声明。结果是缺乏标准化的护理和对这种有效治疗的利用不足。为此,我们召集了一个由 13 名儿科运动障碍专家和 1 名在儿科深部脑刺激方面经验丰富的神经外科医生组成的焦点小组,以回顾最近的文献和当前实践,并提出候选者选择、植入目标部位选择和编程算法的标准化方法。对于小儿肌张力障碍,我们提供了用于 (1) 初始会话和后续会话编程的算法,(2) 解决编程过程中遇到的副作用。我们讨论了常见的副作用、它们如何呈现以及管理建议。本专题综述可作为对使用深部脑刺激治疗儿科肌张力障碍感兴趣的运动障碍专家的资源。

更新日期:2022-09-03
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