In order to enhance osteogenic differentiation and antibacterial property of dental implants, volcano-shaped microporous TiO₂ coatings doped with Cu were fabricated via micro-arc oxidation (MAO) on Ti. Cu-doped coating with different mass ratios of Cu were obtained by changing the concentration of copper acetate in the electrolyte. The structure of Cu-TiO₂ coatings were systematically investigated. Element Copper was uniformly distributed throughout the coating. Compared with TiO₂ coating, the Cu-doped can further improved proliferation of bone mesenchymal stem cells (BMSCs), facilitated osteogenic differentiation. The bacteriostasis experiments demonstrated that Cu-doped TiO₂ coating possess excellent antibacterial property against Staphylococcus aureus (S. aureus) and Porphyromonas gingivalis (P. gingivalis).

为了增强牙种植体的成骨分化和抗菌性能，采用钛微弧氧化（MAO）制备了Cu掺杂火山形微孔TiO _2涂层。通过改变电解液中醋酸铜的浓度，得到不同质量比的Cu掺杂涂层。系统地研究了Cu-TiO ₂涂层的结构。元素铜均匀地分布在整个涂层中。与TiO ₂涂层相比，Cu掺杂可以进一步促进骨间充质干细胞（BMSCs）的增殖，促进成骨分化。抑菌实验表明，Cu掺杂的TiO ₂涂层具有优异的抗菌性能。金黄色葡萄球菌(金黄色葡萄球菌) 和牙龈卟啉单胞菌 (牙龈卟啉单胞菌）。