Multisystemic inflammatory syndrome in children is an inflammatory condition with multiorgan dysfunction that manifest late in the course of Severe acute respiratory syndrome coronavirus 2 infection. We present a 12-year-old boy with a history of fever, vomiting, diarrhoea, and abdominal pain. He developed shock with ventricular dysfunction and pericardial effusion. He was diagnosed with multisystemic inflammatory syndrome in children and treatment with intravenous immunoglobulins, corticosteroids, and tocilizumab proved to be ineffective. Eventually, the patient responded to cyclosporin-A treatment. Multisystemic inflammatory syndrome in children has been treated with immunoglobulins and glucocorticoids and in refractory cases biologics and cyclosporin-A have been used. Intravenous and oral cyclosporin-A seems to be a safe and effective alternative treatment for refractory multisystemic inflammatory syndrome in children patients.

儿童多系统炎症综合征是严重急性呼吸综合征冠状病毒 2 感染病程晚期出现的伴有多器官功能障碍的炎症状态。我们介绍了一名有发烧、呕吐、腹泻和腹痛病史的 12 岁男孩。他出现休克伴心室功能不全和心包积液。他被诊断出患有儿童多系统炎症综合征，静脉注射免疫球蛋白、皮质类固醇和托珠单抗治疗被证明无效。最终，患者对环孢菌素 A 治疗产生了反应。已使用免疫球蛋白和糖皮质激素治疗儿童多系统炎症综合征，在难治性病例中使用生物制剂和环孢菌素 A。