Androgen receptor blockade may have clinical utility in treating cancers other than prostate cancer. Several mouse studies have found that antiandrogen drugs boost the efficacy of immune checkpoint inhibitors and help combat resistance to targeted agents for a variety of tumor types. Clinical trials are underway to assess AR inhibition as an adjunct to multiple forms of cancer therapy.

中文翻译：

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AR 阻滞剂增强其他癌症治疗

雄激素受体阻断可能在治疗前列腺癌以外的癌症方面具有临床用途。几项小鼠研究发现，抗雄激素药物可增强免疫检查点抑制剂的功效，并有助于对抗多种肿瘤类型的靶向药物的耐药性。临床试验正在进行中，以评估 AR 抑制作为多种癌症治疗的辅助手段。