Abstract

This study aimed to investigate the metal-binding effect of fluoride, contained in different commercial toothpaste gels; the study aimed to determine if the toothpastes contained excessive concentrations of fluoride, which result in white spot lesions. A spectrophotometric method that used spectrophotometric reagents, including zinc oxide nanoparticles and iron chloride, was used to determine fluoride distribution; the analysis was based on the selective attack of fluoride ions on metals. Fluoride concentrations between 0 and 1450 ppm were analyzed. Although the iron–fluoride complex was a more sensitive reagent, the zinc–fluoride complex could serve as a suitable alternative to it for fluoride analysis, partly because the method was less time consuming and more stable. The detection and quantification limits obtained from the linear calibration curves of the zinc–fluoride complexes, in deionized water, were 0.191:1 and 0.579:1 w/w ZnO, respectively. A model calibration curve was suggested to detect the unknown products of fluoride degradation. Dentists could use a fluoride treatment similar to the protocol used in this study, to prevent potential enamel demineralization, and exclude physical cavity preparation and restoration.

摘要

本研究旨在研究不同商业牙膏凝胶中所含氟化物的金属结合作用；该研究旨在确定牙膏是否含有过量的氟化物，从而导致白斑损伤。使用分光光度法试剂，包括氧化锌纳米颗粒和氯化铁，用于确定氟化物分布；该分析基于氟离子对金属的选择性攻击。分析了 0 到 1450 ppm 之间的氟化物浓度。尽管铁-氟化物络合物是一种更灵敏的试剂，但锌-氟化物络合物可以作为氟化物分析的合适替代品，部分原因是该方法耗时更少且更稳定。从去离子水中的氟化锌配合物的线性校准曲线获得的检测限和定量限分别为 0.191:1 和 0.579:1 w/w ZnO。建议使用模型校准曲线来检测氟化物降解的未知产物。牙医可以使用类似于本研究中使用的方案的氟化物治疗，以防止潜在的牙釉质脱矿，并排除物理腔准备和修复。