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Cystic hepatic metastases in treatment naïve neuroendocrine tumor: Cytomorphology clubbed with cell block immunocytochemistry clinches the diagnosis
Diagnostic Cytopathology ( IF 1.3 ) Pub Date : 2022-08-27 , DOI: 10.1002/dc.25047
Malvika Shastri 1 , Reetu Kundu 2 , Venkata Subramanian Krishnaraju 3 , Harish Bhujade 4 , Rajan Mani Bhandari 4 , Ashwani Sood 3
Affiliation  

Cystic hepatic lesions encompass a vast spectrum of infectious, non-neoplastic, and neoplastic entities. Most hepatic cysts are benign and asymptomatic, requiring no active intervention. However, symptomatic and malignant cysts need proper evaluation and specific treatment. An accurate preoperative diagnosis is pivotal for patient management. At times, these lesions may mimic, especially symptomatology and radiology, leading to a diagnostic ordeal. We herein present a case of a patient with cystic liver lesions in a treatment naïve neuroendocrine tumor that was a diagnostic dilemma on radiology. Low cellularity of cytology smears made the diagnosis challenging, and cell block immunocytochemistry finally clinched the diagnosis. A timely diagnosis provided on cytology fuelled further work-up, the discovery of primary tumor, and initiation of appropriate therapy.

中文翻译:

治疗初治神经内分泌肿瘤的囊性肝转移:细胞形态学结合细胞块免疫细胞化学确定诊断

囊性肝病变包括范围广泛的感染性、非肿瘤性和肿瘤性实体。大多数肝囊肿是良性和无症状的,不需要积极干预。然而,有症状的恶性囊肿需要适当的评估和特殊的治疗。准确的术前诊断对于患者管理至关重要。有时,这些病变可能会模仿,尤其是症状学和放射学,导致诊断困难。我们在此介绍一例患有囊性肝脏病变的患者,该患者患有未治疗过的神经内分泌肿瘤,这在放射学上是一个诊断难题。细胞学涂片的低细胞度使诊断具有挑战性,细胞块免疫细胞化学最终确定了诊断。及时的细胞学诊断推动了进一步的检查,原发性肿瘤的发现,
更新日期:2022-08-27
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