Background: Currently available evidence favors the combination of chemotherapy with concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (LANPC). However, the optimal timing for additional chemotherapy is unclear. This study was conducted to compare the efficacy and toxicity of induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT) versus concurrent chemoradiotherapy plus adjuvant chemotherapy (CCRT+AC).

中文翻译：

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局部晚期鼻咽癌诱导与辅助化疗联合同步放化疗的比较：一项回顾性队列研究

背景：目前可用的证据支持在局部晚期鼻咽癌 (LANPC) 中联合化疗和同步放化疗。然而，额外化疗的最佳时机尚不清楚。本研究旨在比较诱导化疗加同步放化疗 (IC+CCRT) 与同步放化疗加辅助化疗 (CCRT+AC) 的疗效和毒性。