Toxic epidermal necrolysis (TEN) is a rare and acute life-threatening condition and one of the severe cutaneous adverse drug reactions. There are limited data on TEN from the COVID-19 vaccine regarding its pathogenesis, treatment, and prognosis, particularly in children. We report a case of COVID-19 vaccine-induced TEN and the patient's human leukocyte antigen pharmacogenomic profile.

中文翻译：

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首剂辉瑞-BioNTech (BNT162b2) 疫苗接种后的中毒性表皮坏死松解症和药物基因组学测试

中毒性表皮坏死松解症（TEN）是一种罕见的急性危及生命的疾病，是严重的皮肤药物不良反应之一。关于 COVID-19 疫苗的 10 项关于其发病机制、治疗和预后的数据有限，尤其是在儿童中。我们报告了一例 COVID-19 疫苗诱导的 TEN 和患者的人类白细胞抗原药物基因组图谱。