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Thoracic Duct Lymphangiography via the Testicular Parenchyma in a Rabbit Model
Journal of Vascular and Interventional Radiology ( IF 2.6 ) Pub Date : 2022-08-23 , DOI: 10.1016/j.jvir.2022.08.017
Takayasu Iwai 1 , Akinaga Sonoda 1 , Sayaka Watase 1 , Yoshiyuki Watanabe 1
Affiliation  

This study aimed to establish an animal model for thoracic duct lymphangiography using ethiodized oil. Thoracic duct lymphangiography was performed via the testes in 21 Japanese white rabbits. The testicular parenchyma was punctured by palpation using a 30-gauge, 0.5-inch needle. Ethiodized oil was injected at a rate of 11.41 mL/h until the testicular efferent lymphatic vessels were delineated and then at a rate of 2.85 mL/h until the entire thoracic duct was delineated. Thoracic duct delineation was 100% successful and showed good depiction based on visual scores. The mean ethiodized oil dose administered was 4.59 mL ± 1.41, and the mean time to visualize the entire thoracic duct was 43.7 minutes ± 14.1. The presented model may serve as a method for future preclinical investigation of the thoracic duct anatomy and for thoracic duct interventions.



中文翻译:

在兔模型中通过睾丸实质进行胸导管淋巴管造影

本研究旨在建立使用乙碘化油进行胸导管淋巴管造影的动物模型。通过对 21 只日本白兔的睾丸进行胸导管淋巴管造影术。使用 30 号、0.5 英寸的针通过触诊刺穿睾丸实质。以 11.41 mL/h 的速度注入乙碘化油,直至描绘出睾丸传出淋巴管,然后以 2.85 mL/h 的速度注入直至描绘出整个胸导管。胸导管描绘是 100% 成功的,并且根据视觉评分显示出良好的描绘。给予的平均乙碘化油剂量为 4.59 mL ± 1.41,显示整个胸导管的平均时间为 43.7 分钟 ± 14.1。所提出的模型可作为未来胸导管解剖学临床前研究和胸导管干预的方法。

更新日期:2022-08-23
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