Introduction UK clinical guidelines recommend that provision of Take Home Naloxone (THN) to heroin and other opiate users can reduce mortality and morbidity in this population. Emergency departments (ED) and ambulance staff could provide ideal opportunities for THN distribution, due to regular encounters with patients experiencing opioid overdose. As part of a wider feasibility study for emergency service provision of THN, we explored user perspectives on feasibility and acceptability of THN, based on previous knowledge and experience of overdose. Methods We conducted qualitative, semi-structured interviews with a sample (n=26) of people who use opiates attending drug treatment outpatient clinic or third sector drug organisation in three UK cities. We analysed data using thematic analysis. Results Respondents had significant experience of overdose (experienced personally or witnessed) and high awareness and understanding of overdose management, including personal experience of THN use. Respondents identified some barriers to THN provision at the time of overdose, e.g. reluctance to engage with health professionals at the time of opioid withdrawal but overall were highly supportive of increased access to THN. Service users perceived THN as an acceptable and easy to use intervention, valuing provision of THN via ambulance or ED staff in addition to community provision. THN training and provision gave respondents a sense of self-agency and empowerment and an opportunity to potentially save the lives of others. Respondents wanted more opportunities for friends and family to also undergo training and receive the THN kits. Conclusion People who access services for their opioid use support increased provision of THN from a wider variety of providers including ED and ambulance staff but also extending to other community support services. Extending THN provision to peers and family of people at risk of overdose could also offer additional opportunities to improve outcomes from opioid overdose events.

中文翻译：

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EP12 向面临阿片类药物过量风险的人提供带回家纳洛酮的紧急服务：潜在接受者的观点——一项定性研究

简介 英国临床指南建议向海洛因和其他阿片类药物使用者提供带回家的纳洛酮 (THN) 可以降低该人群的死亡率和发病率。由于经常遇到阿片类药物过量的患者，急诊科 (ED) 和救护人员可以为 THN 分发提供理想的机会。作为 THN 提供紧急服务的更广泛可行性研究的一部分，我们根据以前对过量服用的知识和经验，探讨了用户对 THN 的可行性和可接受性的看法。方法 我们在三个英国城市对参加药物治疗门诊或第三部门药物组织的阿片类药物使用者样本（n=26）进行了定性、半结构化访谈。我们使用主题分析来分析数据。结果 受访者有大量的过量用药经验（亲身经历或目击），并且对过量用药管理有很高的认识和理解，包括个人使用 THN 的经验。受访者在过量服用 THN 时发现了一些障碍，例如在阿片类药物戒断时不愿与卫生专业人员接触，但总体上高度支持增加获得 THN 的机会。服务使用者认为 THN 是一种可接受且易于使用的干预措施，除了社区提供外，还重视通过救护车或 ED 工作人员提供 THN。THN 培训和提供给受访者一种自我代理感和赋权感，以及一个可能挽救他人生命的机会。受访者希望朋友和家人有更多机会接受培训并获得 THN 套件。结论 因使用阿片类药物而获得服务的人支持从更广泛的提供者（包括 ED 和救护车工作人员）提供更多的 THN，但也扩展到其他社区支持服务。将 THN 提供给有过量服用风险的同龄人和家庭也可以提供额外的机会来改善阿片类药物过量事件的结果。