AIF1+CSF1R+ MSCs, induced by TNF-α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis,Hepatology

当前位置： X-MOL 学术 › Hepatology › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

AIF1+CSF1R+ MSCs, induced by TNF-α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis
Hepatology ( IF 12.9 ) Pub Date : 2022-08-21 , DOI: 10.1002/hep.32738
Chen Zong _{1,

2} , Yan Meng _{1,

2} , Fei Ye _{1,

2} , Xue Yang _{1,

2} , Rong Li ₁ , Jinghua Jiang _{1,

2} , Qiudong Zhao _{1,

2} , Lu Gao _{1,

2} , Zhipeng Han _{1,

2} , Lixin Wei _{1,

2}

Affiliation

Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver. Chronic inflammation is regarded as the major trait of primary liver cancer. However, the characteristics of endogenous MSCs in the inflammatory environment and their role in the occurrence of liver cancer remain obscure.

中文翻译：