Study Objective

We sought to determine whether pilonidal disease (PD) is associated with polycystic ovarian syndrome (PCOS) in adolescent females.

Design

Retrospective cohort study

Setting

Urban tertiary children's hospital

Participants

All girls aged 12 to 21 who received a diagnosis of PD and/or PCOS from 2012 to 2019

Interventions

Treatment for PCOS and PD

Main Outcome Measures

The variables analyzed included age, race/ethnicity, body mass index, age at menarche, tobacco use, payer status, treatment of PCOS and PD, and serum markers of hyperandrogenism and metabolic syndrome.

Results

During the study period, 100,043 patients presented to an urban tertiary medical center. Of these patients, 966 were diagnosed with PD, and 219 were diagnosed with both PD and PCOS. Compared with patients with only PD, patients with both diagnoses had a higher body mass index (31.4 vs 27.4 kg/m²; P < .01) and were older (18.76 vs 18.30 years; P = .003). The prevalence ratio for patients with PD having PCOS per the original Rotterdam criteria was 26.1 (CI, 22.0-31.0) and 28.7 (CI, 24.3-33.9) for having PCOS per the modified Rotterdam criteria. Patients with both diagnoses were less likely to receive intervention for PD (OR = 0.22; CI, 0.13-0.37; P < .001).

Conclusions

Adolescent females diagnosed with PD are likely to demonstrate features of PCOS. PCOS treatment could positively alter the disease course of PD. As such, surgical providers should consider referring adolescent females with PD to endocrinologists, gynecologists, and adolescent medicine specialists for evaluation of PCOS.

中文翻译：

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建立青春期女性多囊卵巢综合征与藏毛病之间的关联

学习目标

我们试图确定藏毛病 (PD) 是否与青春期女性的多囊卵巢综合征 (PCOS) 相关。

设计

回顾性队列研究

环境

市区三级儿童医院

参加者

2012 年至 2019 年诊断为 PD 和/或 PCOS 的所有 12 至 21 岁女孩

干预措施

PCOS 和 PD 的治疗

主要观察指标

分析的变量包括年龄、种族/族裔、体重指数、初潮年龄、烟草使用、支付状态、PCOS 和 PD 的治疗，以及高雄激素血症和代谢综合征的血清标志物。

结果

在研究期间，有 100,043 名患者就诊于城市三级医疗中心。在这些患者中，966 人被诊断为 PD，219 人同时被诊断为 PD 和 PCOS。与仅患有 PD 的患者相比，同时患有两种疾病的患者体重指数更高（31.4 vs 27.4 kg/m ² ；P < .01）并且年龄更大（18.76 vs 18.30 岁；P  = .003）。根据原始鹿特丹标准，患有 PCOS 的 PD 患者的患病率分别为 26.1 (CI, 22.0-31.0) 和 28.7 (CI, 24.3-33.9)，根据修改后的鹿特丹标准。具有这两种诊断的患者不太可能接受 PD 干预（OR = 0.22；CI，0.13-0.37；P < .001）。

结论

被诊断患有 PD 的青春期女性很可能表现出 PCOS 的特征。PCOS 治疗可以积极改变 PD 的病程。因此，外科医生应考虑将患有 PD 的青春期女性转诊给内分泌学家、妇科医生和青春期医学专家，以评估 PCOS。