The level of neuromuscular blockade can be assessed by subjective (qualitative) and objective (quantitative) methods. This study aims to compare the dosage of the neuromuscular blocking agents (NMBA) rocuronium and the need for reversion by sugammadex between those methods. A retrospective, observational analysis was conducted. In the tactile qualitative-neuromuscular monitoring-group (tactile NMM) (n = 244), muscle contractions were assessed tactilely. In the quantitative neuromuscular monitoring-group (n = 295), contractions were accessed using an acceleromyograph. Primary endpoints were dosage of rocuronium per minute operation-time (milligram per kilogram bodyweight per minute (mg/kgBW/min)), count of repeated rocuronium administrations and use of sugammadex. Secondary endpoints were: NMM use before repeated NMBA application or extubation, time to extubation, post-operative oxygen demand. A total of n = 539 patients were included. n = 244 patients were examined with tactile NMM and 295 patients by quantitative NMM. Quantitative NMM use resulted in significantly lower rocuronium dosing (tactile NMM: 0.01 (± 0.007) mg/kgBW/min vs. quantitative NMM: 0.008 (± 0.006) mg/kgBW/min (p < 0.001)). In quantitative NMM use fewer repetitions of rocuronium application were necessary (tactile NMM: 83% (n = 202) vs. quantitative NMM: 71% (n = 208) p = 0.007). Overall, 24% (n = 58) in the tactile NMM-group, and 20% (n = 60) in the quantitative NMM-group received sugammadex ((p = 0.3), OR: 1.21 (0.81–1.82)). Significantly fewer patients in the quantitative NMM-group required oxygen-supply postoperative (quantitative NMM: 43% (n = 120)) vs. tactile NMM: 57% (n = 128)) (p = 0.002). The use of quantitative assessment of NMBA results in a lower overall dosage and requires fewer repetitions of rocuronium application. Therefore, quantitative monitoring systems should be used to monitor NMBA intraoperatively to reduce NMBA dosing, while achieving continuous neuromuscular blockade.

神经肌肉阻滞的水平可以通过主观（定性）和客观（定量）方法来评估。本研究旨在比较神经肌肉阻滞剂 (NMBA) 罗库溴铵的剂量以及这些方法之间舒更葡糖逆转的需要。进行了回顾性观察分析。在触觉定性神经肌肉监测组（触觉 NMM）（n = 244）中，通过触觉评估肌肉收缩。在定量神经肌肉监测组（n = 295）中，使用肌加速描记器记录收缩情况。主要终点是每分钟手术时间罗库溴铵的剂量（每分钟每公斤体重毫克数（mg/kgBW/min））、罗库溴铵重复给药次数和舒更葡糖的使用次数。次要终点为：重复 NMBA 应用或拔管前 NMM 使用情况、拔管时间、术后需氧量。总共纳入 n = 539 名患者。 n = 244 名患者接受了触觉 NMM 检查，295 名患者接受了定量 NMM 检查。定量 NMM 的使用导致罗库溴铵剂量显着降低（触觉 NMM：0.01 (± 0.007) mg/kgBW/min 对比定量 NMM：0.008 (± 0.006) mg/kgBW/min ( p < 0.001)）。在定量 NMM 中，需要减少罗库溴铵应用的重复次数（触觉 NMM：83% (n = 202) 对比定量 NMM：71% (n = 208) p = 0.007）。总体而言，触觉 NMM 组中的 24% (n = 58) 和定量 NMM 组中的 20% (n = 60) 接受了舒更葡糖 (( p = 0.3)，OR：1.21 (0.81–1.82)）。定量 NMM 组术后需要供氧的患者明显较少（定量 NMM：43% (n = 120)），而触觉 NMM：57% (n = 128)）（ p = 0.002）。 使用 NMBA 定量评估可降低总体剂量，并减少罗库溴铵应用的重复次数。因此，术中应使用定量监测系统监测NMBA，以减少NMBA剂量，同时实现持续的神经肌肉阻滞。