This work attempts to evaluate dermal exposure (DE) of farm workers to dimethoate after 4 h of routine application to a lemon plantation. Dimethoate was measured on the workers’ clothes as well as in stratum corneum (SC) and in saliva. In vitro permeation tests (IVPT) were performed through rat, pig and human skin and pig buccal, esophageal and sublingual mucosas. The mean of dimethoate DE was 342.19 ± 487.14 mg/d, the percentage of toxic dose per hour was higher than the other pesticides, and the SC penetration factors ranged between 0.5 and 14.81 and 0.05–53.96 % for back of neck and arms respectively. In the supporting IVPT study, dimethoate absorption through human skin was 14.75 % and the default value in the absence of experimental data for this product is 70%. These results show that in family farming the deficiency of correct clothing during the application of pesticides leaves workers more vulnerable.

这项工作试图评估农场工人在柠檬种植园常规施用 4 小时后对乐果的皮肤暴露 (DE)。在工人的衣服以及角质层(SC) 和唾液中测量了乐果。体外通过大鼠、猪和人的皮肤以及猪的颊、食道和舌下粘膜进行渗透测试（IVPT）。乐果 DE 平均值为 342.19 ± 487.14 mg/d，每小时中毒剂量百分比高于其他农药，SC 渗透因子分别在 0.5 和 14.81 之间以及颈后和手臂的 0.05-53.96 % 之间。在支持性的 IVPT 研究中，乐果通过人体皮肤的吸收率为 14.75%，并且在没有该产品的实验数据的情况下，默认值为 70%。这些结果表明，在家庭农业中，在施用杀虫剂期间缺乏正确的衣服会使工人更容易受到伤害。