-medicate for pain, opioid use disorder, and other mental health conditions. While implications of kratom use in patients with chronic pain and/or opioid use disorder have been published, information on perianesthetic implications is lacking. Anesthesiologists should be informed about kratom, including the potential for unexpected physiologic derangements and adverse drug interactions resulting from complex pharmacologic activity, cytochrome P450 interactions, and common adulterations of the drug that may result in unpredictable clinical effects. This article explores the relevance of kratom to perioperative anesthetic care, including suggestions for anesthesiologists extrapolated from published information in nonoperative settings that may improve patient safety in individuals using kratom....

中文翻译：

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Kratom 的叙事回顾，一种具有围产期影响的新兴精神活性物质

- 治疗疼痛、阿片类药物使用障碍和其他心理健康状况。虽然 kratom 使用对慢性疼痛和/或阿片类药物使用障碍患者的影响已经公布，但缺乏关于围麻醉期影响的信息。麻醉师应了解 kratom，包括潜在的意外生理紊乱和由复杂的药理活性、细胞色素 P450 相互作用以及可能导致不可预测的临床效果的药物常见掺假引起的不良药物相互作用。本文探讨了卡痛叶与围手术期麻醉护理的相关性，包括对麻醉师的建议，这些建议是根据非手术环境中已发表的信息推断的，这些信息可能会提高使用卡痛叶的患者的安全性……