Beta-alanine (BA) supplementation increases muscle carnosine, an abundant endogenous antioxidant and pH buffer in skeletal muscle. Carnosine loading promotes exercise capacity in healthy older adults. As patients with chronic obstructive pulmonary disease (COPD) suffer from elevated exercise-induced muscle oxidative/carbonyl stress and acidosis, and from reduced muscle carnosine stores, it was investigated whether BA supplementation augments muscle carnosine and induces beneficial changes in exercise capacity, quadriceps function, and muscle oxidative/carbonyl stress in patients with COPD.

中文翻译：

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12 周口服 β-丙氨酸补充剂对慢性阻塞性肺病患者的疗效：一项双盲、随机、安慰剂对照试验

β-丙氨酸 (BA) 补充剂可增加肌肉肌肽，这是骨骼肌中丰富的内源性抗氧化剂和 pH 缓冲剂。肌肽负荷促进健康老年人的运动能力。由于患有慢性阻塞性肺疾病 (COPD) 的患者患有运动引起的肌肉氧化/羰基应激和酸中毒，以及肌肉肌肽储存减少，因此研究了补充 BA 是否会增加肌肉肌肽并诱导运动能力、股四头肌功能的有益变化和 COPD 患者的肌肉氧化/羰基应激。