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Self-Assembled Aza-Boron-Dipyrromethene for Ferroptosis-Boosted Sonodynamic Therapy
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2022-08-18 , DOI: 10.1002/anie.202210174
Changwen You 1 , Xingguang Li 2 , Dongqiong Wang 1 , Hongzhong Chen 3 , Lei Liang 1 , Yu Chen 1 , Yanli Zhao 3 , Huijing Xiang 1, 3
Affiliation  

Cysteine-responsive Aza-boron-dipyrromethene organic nanoparticles are designed to induce ferroptosis and serve as sonosensitizer. These nanoparticles promote ferroptosis-enhanced sonodynamic therapy, inducing cancer cell death and tumor growth suppression.

中文翻译:

自组装氮杂硼二吡咯亚甲基用于铁死亡促进的声动力治疗

半胱氨酸响应性氮杂硼二吡咯亚甲基有机纳米颗粒旨在诱导铁死亡并用作声敏剂。这些纳米颗粒促进了铁死亡增强的声动力疗法,诱导癌细胞死亡和肿瘤生长抑制。
更新日期:2022-08-18
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