A protocol for a prospective observational cohort study to investigate the effect of frailty on long-term outcomes in older adults admitted with trauma. Patients aged 65 years and older admitted to the Severn Major Trauma Centre at North Bristol NHS Trust in England between November 2018 and September 2019, will be followed up at 4-years. The objective is to determine if there is an association between Clinical Frailty Scale and mortality at 4 years after admission to hospital with a traumatic injury. The primary outcome will be mortality as measured by time from hospital admission to death. Analyses will be adjusted for other factors shown to be associated with mortality, using a mixed-effects multivariable Cox proportional hazards model.

中文翻译：

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一项针对严重受伤的老年创伤患者的长期前瞻性队列研究

一项前瞻性观察性队列研究的方案，旨在调查虚弱对接受创伤的老年人长期结局的影响。2018 年 11 月至 2019 年 9 月期间在英格兰北布里斯托 NHS 信托基金的 Severn 重大创伤中心收治的 65 岁及以上的患者将接受 4 年随访。目的是确定临床虚弱量表与因外伤入院后 4 年的死亡率之间是否存在关联。主要结果将是从入院到死亡的时间来衡量的死亡率。使用混合效应多变量 Cox 比例风险模型，将针对与死亡率相关的其他因素调整分析。