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Autistic traits heighten sensitivity to rejection-induced social pain
Annals of the New York Academy of Sciences ( IF 4.1 ) Pub Date : 2022-08-17 , DOI: 10.1111/nyas.14880
Xinxin Lin 1 , Shiwei Zhuo 1 , Zhouan Liu 1 , Junsong Fan 1 , Weiwei Peng 1
Affiliation  

Autistic traits—subclinical forms of characteristics associated with autism spectrum disorders—are associated with poor social interactions and high risks for mental health disorders. We hypothesized that altered sensitivity to social rejection is an important contributor to psychological distress observed among individuals with high autistic traits. Experiment 1 adopted a social-judgment task and compared behavioral and neural activity in response to social rejection between participants exhibiting either high or low autistic traits (HAT and LAT, respectively). Rejection-induced hurt feelings, P3 amplitudes, and θ-oscillation magnitudes were greater in the HAT group than in the LAT group. Mediation analysis indicated that autistic traits heighten rejection-induced social pain through increasing frontal-midline θ-oscillations. Responses to nonsocial feedback in the age-judgment task were comparable, confirming that the between-group differences were specific to social negative feedback. Experiment 2 assessed the association between autistic traits, rejection sensitivity, and psychological distress among randomly recruited participants. Results showed that autistic traits affected depressive/anxious symptomatology partially through heightened rejection sensitivity. Therefore, autistic traits heighten sensitivity to rejection-induced social pain that leads to psychological distress. This finding will help facilitate the development of strategies for coping with social pain and improving mental health for individuals with high autistic traits.

中文翻译:

自闭症特征提高了对拒绝引起的社会痛苦的敏感性

自闭症特征——与自闭症谱系障碍相关的亚临床特征形式——与不良的社会交往和精神健康障碍的高风险有关。我们假设对社会排斥的敏感度改变是导致具有高度自闭症特征的个体心理困扰的重要因素。实验 1 采用了一项社会判断任务,并比较了表现出高或低自闭症特征(分别为 HAT 和 LAT)的参与者对社会排斥反应的行为和神经活动。HAT 组的拒绝引起的伤害感受、P3 振幅和 θ 振荡幅度大于 LAT 组。中介分析表明,自闭症特征通过增加额叶中线 θ 振荡来加剧拒绝引起的社会痛苦。在年龄判断任务中对非社会反馈的反应具有可比性,证实组间差异特定于社会负反馈。实验 2 评估了随机招募的参与者中自闭症特征、拒绝敏感性和心理困扰之间的关联。结果表明,自闭症特征部分通过提高排斥敏感性来影响抑郁/焦虑症状。因此,自闭症特征提高了对拒绝引起的社会痛苦的敏感性,从而导致心理困扰。这一发现将有助于促进具有高度自闭症特征的个体应对社会痛苦和改善心理健康的策略的发展。确认组间差异特定于社会负面反馈。实验 2 评估了随机招募的参与者中自闭症特征、拒绝敏感性和心理困扰之间的关联。结果表明,自闭症特征部分通过提高排斥敏感性来影响抑郁/焦虑症状。因此,自闭症特征提高了对拒绝引起的社会痛苦的敏感性,从而导致心理困扰。这一发现将有助于促进具有高度自闭症特征的个体应对社会痛苦和改善心理健康的策略的发展。确认组间差异特定于社会负面反馈。实验 2 评估了随机招募的参与者中自闭症特征、拒绝敏感性和心理困扰之间的关联。结果表明,自闭症特征部分通过提高排斥敏感性来影响抑郁/焦虑症状。因此,自闭症特征提高了对拒绝引起的社会痛苦的敏感性,从而导致心理困扰。这一发现将有助于促进具有高度自闭症特征的个体应对社会痛苦和改善心理健康的策略的发展。结果表明,自闭症特征部分通过提高排斥敏感性来影响抑郁/焦虑症状。因此,自闭症特征提高了对拒绝引起的社会痛苦的敏感性,从而导致心理困扰。这一发现将有助于促进具有高度自闭症特征的个体应对社会痛苦和改善心理健康的策略的发展。结果表明,自闭症特征部分通过提高排斥敏感性来影响抑郁/焦虑症状。因此,自闭症特征提高了对拒绝引起的社会痛苦的敏感性,从而导致心理困扰。这一发现将有助于促进具有高度自闭症特征的个体应对社会痛苦和改善心理健康的策略的发展。
更新日期:2022-08-17
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