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Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus
Emerging Infectious Diseases ( IF 7.2 ) Pub Date : 2022-08-16 , DOI: 10.3201/eid2809.220509
Kaye Quizon , Kimberly Holloway , Mahmood Iranpour , Bryce M Warner , Yvon Deschambault , Geoff Soule , Kevin Tierney , Darwyn Kobasa , Angela Sloan , David Safronetz

We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus mice, the established primary hosts for SNV.



中文翻译:


Sin Nombre 病毒对白鼠属啮齿类动物的实验感染



我们证明 6 种不同的白鼠啮齿类动物能够实验性感染辛诺伯正汉坦病毒 (SNV)。在所有 6 个物种的成员中均检测到病毒 RNA 和 SNV 抗体。 P. leucopus小鼠表现出明显高于P. maniculatus小鼠 SNV 的既定主要宿主)的病毒和抗体滴度。

更新日期:2022-08-17
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