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Cardiovascular Effects of Home Dialysis Therapies: A Scientific Statement From the American Heart Association
Circulation ( IF 35.5 ) Pub Date : 2022-08-15 , DOI: 10.1161/cir.0000000000001088
Mark J. Sarnak , Bourne L. Auguste , Edwina Brown , Alexander R. Chang , Glenn M. Chertow , Mary Hannan , Charles A. Herzog , Annie-Claire Nadeau-Fredette , Wai Hong Wilson Tang , Angela Yee-Moon Wang , Daniel E. Weiner , Christopher T. Chan ,

Cardiovascular disease is the leading cause of morbidity and mortality in patients with end-stage kidney disease. Currently, thrice-weekly in-center hemodialysis for 3 to 5 hours per session is the most common therapy worldwide for patients with treated kidney failure. Outcomes with thrice-weekly in-center hemodialysis are poor. Emerging evidence supports the overarching hypothesis that a more physiological approach to administering dialysis therapy, including in the home through home hemodialysis or peritoneal dialysis, may lead to improvement in several cardiovascular risk factors and cardiovascular outcomes compared with thrice-weekly in-center hemodialysis. The Advancing American Kidney Health Initiative, which has a goal of increasing the use of home dialysis, is aligned with the American Heart Association’s 2024 mission to champion a full and healthy life and health equity. We conclude that incorporation of interdisciplinary care models to increase the use of home dialysis therapies in an equitable manner will contribute to the ultimate goal of improving outcomes for patients with kidney failure and cardiovascular disease.

中文翻译:

家庭透析疗法对心血管的影响:美国心脏协会的科学声明

心血管疾病是终末期肾病患者发病率和死亡率的主要原因。目前,每周三次的中心血液透析,每次 3 至 5 小时,是全球治疗肾衰竭患者最常见的治疗方法。每周三次的中心血液透析的结果很差。新出现的证据支持一个总体假设,即与每周三次的中心血液透析相比,采用更生理的透析治疗方法,包括在家中通过家庭血液透析或腹膜透析,可能会改善一些心血管危险因素和心血管结局。推进美国肾脏健康倡议,其目标是增加家庭透析的使用,符合美国心脏协会的 2024 年使命,即倡导全面健康的生活和健康公平。我们得出结论,纳入跨学科护理模式以公平地增加家庭透析疗法的使用将有助于改善肾衰竭和心血管疾病患者预后的最终目标。
更新日期:2022-08-15
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