Visible-Light-Induced Acylation/Arylation of Alkenes via Aryl Migration/Desulfonylation,European Journal of Organic Chemistry

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Visible-Light-Induced Acylation/Arylation of Alkenes via Aryl Migration/Desulfonylation
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2022-08-11 , DOI: 10.1002/ejoc.202200793
Zhen-Tao Luo ₁ , Jian-Hong Fan ₁ , Bi-Quan Xiong ₁ , Yu Liu ₂ , Peng-Fei Huang ₁

Affiliation

A new photoinduced acylation/arylation of N-(arylsulfonyl)acrylamide with acyl oxime esters through a nitrogen-centered radical protocol has been disclosed for efficient preparation of functionalized indolin-2-ones, which proceeds through a cascade acyl radical addition of carbon-carbon double bond, aryl migration, desulfonylation, and intramolecular cyclization sequence. This redox-neutral strategy features excellent selectivity, good substituent tolerance, and wide substrate scope.

中文翻译：

通过芳基迁移/脱磺酰化的可见光诱导的烯烃酰化/芳基化

一种新的光诱导酰化/芳基化N- (芳基磺酰基)丙烯酰胺与酰基肟酯通过以氮为中心的自由基方案用于有效制备官能化二氢吲哚-2-酮，其通过碳-碳的级联酰基自由基加成进行双键、芳基迁移、去磺酰化和分子内环化序列。这种氧化还原中性策略具有优异的选择性、良好的取代基耐受性和广泛的底物范围。

更新日期：2022-08-11

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