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Accessible bioengineered corneal tissue to address a blinding disease globally
Nature Biotechnology ( IF 33.1 ) Pub Date : 2022-08-11 , DOI: 10.1038/s41587-022-01409-9


Porcine dermal collagen was chemically and photochemically bioengineered into an implantable tissue mimicking the human corneal extracellular matrix. The implant presents a simpler and safer method than donor cornea transplantation while delivering equivalent outcomes, and has restored vision to people with advanced keratoconus in resource-limited regions, where the burden of blindness is highest.

中文翻译:

可及的生物工程角膜组织可在全球范围内解决致盲性疾病

猪真皮胶原蛋白经过化学和光化学生物工程改造成为模仿人类角膜细胞外基质的可植入组织。该植入物提供了一种比供体角膜移植更简单、更安全的方法,同时提供了相同的结果,并在资源有限、失明负担最高的地区为患有晚期圆锥角膜的人恢复了视力。
更新日期:2022-08-12
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