Purpose To explore the associations between hand grip strength (HGS) and ocular parameters and diseases. Design Population-based cohort study. Methods Participants of the Ural Eye and Medical Study, including 5899 (80.5%) out of 7328 eligible individuals aged 40+ years, underwent systemic and ophthalmological examinations including dynamometric HGS measurement. Results The study included 5381 (90.4%) individuals (age: 58.6±10.6 years; range: 40–94 years) with HGS measurements. Higher HGS (mean: 30.6±11.7 dekaNewton) correlated (multivariable analysis) with better visual acuity (beta: 0.02, p=0.02), longer ocular axial length (beta: 0.03, p=0.003), higher intraocular pressure (beta: 0.03, p=0.001), thicker peripapillary retinal nerve fibre layer (beta: 0.03, p=0.001) and lower prevalence of diabetic retinopathy (beta: −0.03, p=0.007), after adjusting for younger age, male sex, Russian ethnicity, higher body height and waist to hip ratio, higher educational level, higher physical total score, lower smoking package years, higher serum concentration of haemoglobin, higher prothrombin index, lower leucocyte cell count, lower prevalence of non-alcoholic fatty liver disease, lower depression score and lower prevalence of arthritis. In the model, HGS was not correlated with prevalence of nuclear cataract (p=0.38), cortical cataract (p=0.67), subcapsular posterior cataract (p=0.50), open-angle glaucoma (p=0.22) or angle-closure glaucoma (p=0.27). Conclusions and relevance In addition to parameters such as lower physical activity, higher depression score and worse general health status, a reduced HGS is associated with visual impairment, shorter axial length, lower intraocular pressure, thinner peripapillary retinal nerve fibre layer and higher prevalence of diabetic retinopathy. HGS dynamometry or a handshake may provide the ophthalmologist additional clinical information about the general health and ocular parameters of the patient. Data are available upon reasonable request.

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握力与眼部关联：乌拉尔眼科与医学研究

目的 探讨握力（HGS）与眼部参数和疾病之间的关联。设计基于人群的队列研究。方法 乌拉尔眼科和医学研究的参与者，包括 7328 名 40 岁以上合格个体中的 5899 名（80.5%），接受了系统和眼科检查，包括动态 HGS 测量。结果 该研究纳入了 5381 名 (90.4%) 进行了 HGS 测量的个体（年龄：58.6±10.6 岁；范围：40-94 岁）。较高的 HGS（平均值：30.6±11.7 dekaNewton）与较好的视力（β：0.02，p=0.02）、较长的眼轴长度（β：0.03，p=0.003）、较高的眼压（β：0.03）相关（多变量分析） ，p=0.001），视乳头周围视网膜神经纤维层较厚（β：0.03，p=0.001），糖尿病视网膜病变患病率较低（β：-0.03，p=0.007），调整年龄、男性、俄罗斯种族后，身高和腰臀比较高、受教育程度较高、体能总分较高、吸烟年限较低、血清血红蛋白浓度较高、凝血酶原指数较高、白细胞计数较低、非酒精性脂肪肝患病率较低、抑郁症较低评分和较低的关节炎患病率。在模型中，HGS 与核性白内障 (p=0.38)、皮质性白内障 (p=0.67)、后囊下白内障 (p=0.50)、开角型青光眼 (p=0.22) 或闭角型青光眼的患病率不相关（p=0.27）。结论和相关性 除了体力活动较低、抑郁评分较高和总体健康状况较差等参数外，HGS 降低还与视力障碍、眼轴较短、眼压较低、视乳头周围视网膜神经纤维层较薄以及糖尿病患病率较高相关。视网膜病变。HGS 测功或握手可以为眼科医生提供有关患者一般健康状况和眼部参数的额外临床信息。数据可根据合理要求提供。