当前位置: X-MOL 学术Clin. Interventions Aging › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Calanus Oil Supplementation Does Not Further Improve Short-Term Memory or Brain-Derived Neurotrophic Factor in Older Women Who Underwent Exercise Training
Clinical Interventions in Aging ( IF 3.5 ) Pub Date : 2022-08-13 , DOI: 10.2147/cia.s368079
Klára Daďová 1 , Miroslav Petr 2 , James J Tufano 2 , Lenka Sontáková 2 , Eva Krauzová 3, 4 , Marek Štěpán 3 , Michaela Šiklová 3 , Michal Šteffl 2
Affiliation  

Purpose: In our study, we examined changes in short-term episodic memory and brain-derived neurotrophic factor (BDNF) in women after an exercise program alone or in combination with omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation.
Patients and Methods: Fifty-five healthy elderly women (65– 80 years) were randomly split into two groups: in the first group were women attending an exercise program while taking wax esters-rich oil (Calanus) supplementation (n = 28) and in the other group were women undergoing the same exercise program while taking placebo (n = 27). The 16-week exercise program consisted of functional circuit training (twice a week) and Nordic walking lessons (once a week). Short-term episodic memory was evaluated by the Czech screening Test “Pojmenování OBrázk&uring A jejich Vybavení” (POBAV) baseline and after the program lasting 16 weeks.
Results: Our results show that short-term memory significantly improved following the exercise program, but there was no added value in using n-3 PUFA supplements. BDNF values did not differ between baseline and follow-up in either group. However, there was a statistically significant positive relationship between relative change (%) in the POBAV test and VO2peak in the placebo group (r = 0.49).
Conclusion: Despite the added value of n-3 PUFA supplementation not being proven, our results may strengthen the importance of physical activity in averting age-related memory decline and dementia.

Keywords: cognitive function, n-3 PUFA, physical activity, aging, circuit training, Nordic walking


中文翻译:

Calanus 油补充剂不会进一步改善接受过运动训练的老年妇女的短期记忆或脑源性神经营养因子

目的:在我们的研究中,我们检查了女性在单独运动计划或与 omega-3 多不饱和脂肪酸 (n-3 PUFA) 补充剂组合后短期情景记忆和脑源性神经营养因子 (BDNF) 的变化。
患者和方法:55 名健康的老年女性(65-80 岁)被随机分成两组:第一组是参加锻炼计划同时服用富含蜡酯的油(Calanus)补充剂的女性(n = 28),另一组是是女性在服用安慰剂的同时接受相同的锻炼计划(n = 27)。为期 16 周的锻炼计划包括功能性循环训练(每周两次)和越野行走课程(每周一次)。短期情景记忆通过捷克筛查测试“Pojmenování OBrázk&uring A jejich Vybavení” (POBAV) 基线和持续 16 周的程序进行评估。
结果:我们的结果表明,锻炼计划后短期记忆显着改善,但使用 n-3 PUFA 补充剂没有附加价值。BDNF 值在两组的基线和随访中没有差异。然而,POBAV 测试的相对变化 (%) 与安慰剂组的 VO 2峰值之间存在统计学上显着的正相关关系(r = 0.49)。
结论:尽管补充 n-3 PUFA 的附加价值尚未得到证实,但我们的结果可能会加强身体活动在避免与年龄相关的记忆力下降和痴呆方面的重要性。

关键词:认知功能,n-3 PUFA,体力活动,衰老,循环训练,越野行走
更新日期:2022-08-12
down
wechat
bug