An accurate fully automated panel of plasma biomarkers for Alzheimer's disease,Alzheimer's & Dementia

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An accurate fully automated panel of plasma biomarkers for Alzheimer's disease
Alzheimer's & Dementia ( IF 13.0 ) Pub Date : 2022-08-11 , DOI: 10.1002/alz.12751
Sebastian Palmqvist _{1,

2} , Erik Stomrud _{1,

2} , Nicholas Cullen ₁ , Shorena Janelidze ₁ , Ekaterina Manuilova ₃ , Alexander Jethwa ₃ , Tobias Bittner ₄ , Udo Eichenlaub ₃ , Ivonne Suridjan ₅ , Gwendlyn Kollmorgen ₃ , Matthias Riepe ₆ , Christine A F von Arnim ₇ , Hayrettin Tumani ₈ , Klaus Hager ₉ , Fedor Heidenreich ₁₀ , Niklas Mattsson-Carlgren _{1,

11,

12} , Henrik Zetterberg _{13,

14,

15,

16,

17} , Kaj Blennow _{13,

14} , Oskar Hansson _{1,

2}

Affiliation

Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden.
Memory Clinic, Skåne University Hospital, Malmö, Sweden.
Roche Diagnostics GmbH, Penzberg, Germany.
F. Hoffmann-La Roche AG, Basel, Switzerland.
Roche Diagnostics International Ltd, Rotkreuz, Switzerland.
Division of Geriatric Psychiatry, Ulm University, Ulm, Germany.
Division of Geriatrics, University Medical Center Göttingen, Georg-August-University, Goettingen, Germany.
Department of Neurology, University Hospital of Ulm, Ulm, Germany.
Institute for General Medicine and Palliative Medicine, Hannover Medical School, Hannover, Germany.
Department of Neurology and Clinical Neurophysiology, Diakovere Krankenhaus Henriettenstift, Hannover, Germany.
Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.
Department of Neurology, Skåne University Hospital, Lund, Sweden.
Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.
Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.
UK Dementia Research Institute at UCL, London, UK.
Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China.

There is a great need for fully automated plasma assays that can measure amyloid beta (Aβ) pathology and predict future Alzheimer's disease (AD) dementia.

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