Summary: In this issue of Cancer Discovery, Drewes and colleagues demonstrate a surprising role for the common gut pathogen Clostridioides difficile in driving colorectal cancer in preclinical models through the bacterial toxin–dependent reprogramming of the epithelial and immune compartments. See related article by Drewes et al., p. 1873 (3).

中文翻译：

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隐藏在众目睽睽之下：结直肠癌的新型微生物驱动因素？

摘要：在本期《癌症发现》中，Drewes 及其同事证明了常见肠道病原体艰难梭菌在临床前模型中通过上皮和免疫区室的细菌毒素依赖性重编程在驱动结直肠癌中发挥着令人惊讶的作用。参见 Drewes 等人的相关文章，第 17 页。1873（3）。