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Phenotypic Frailty Score Predicts Perioperative Outcomes for Geriatric Total Joint Arthroplasty
Orthopedics ( IF 1.1 ) Pub Date : 2022-08-10 , DOI: 10.3928/01477447-20220805-04
Sahir S Pervaiz , Scott J Douglas , Oliver C Sax , Austin Nabet , Ruben G Monarrez , Ethan A Remily , Thomas Novack , James Nace , Ronald E Delanois

Various assessment tools are often used to predict perioperative morbidity among patients older than 75 years who undergo total joint arthroplasty. Yet, few studies describe the use of phenotypic frailty as a predictor for outcomes. The goal of this study was to assess phenotypic frailty with the Sinai Abbreviated Geriatric Evaluation (SAGE) and compare its utility with established assessment tools used in practice. We specifically asked: (1) Can SAGE predict 30-day outcomes, including postoperative delirium? (2) Can SAGE determine the risk of prolonged hospital length of stay? (3) Is SAGE predictive for 30-day readmissions? (4) Can SAGE determine the risk of discharge to a specialized facility? Patients undergoing total hip arthroplasty and total knee arthroplasty were evaluated with the American Association of Anesthesiologists Physical Status (ASA), Charlson Comorbidity Index (CCI), 5-point Modified Frailty Score (5-FS), and SAGE. Assessment scores were determined for each patient, and every incremental change in score was used to predict the likelihood of perioperative complications. A receiver operating characteristic analysis was also performed to calculate testing sensitivity for each assessment tool. The SAGE scores were more likely to predict 30-day complications (odds ratio [95 CI], 2.21 [1.32–3.70]), postoperative delirium (6.40 [1.78–23.03]), and length of stay greater than 2 days (3.90 [1.00–15.7]) compared with ASA, CCI, and 5-FS values. The SAGE scores were not predictive of readmission (1.77 [0.66–4.72]) or discharge to a specialized facility (1.48 [0.80–2.75]). The SAGE score was a more sensitive predictor (area under the curve, 0.700) for perioperative morbidity compared with ASA (0.638), CCI (0.662), and 5-FS (0.644) values. Therefore, SAGE scores can reliably assess risk of perioperative morbidity and may have better clinical utility than ASA, CCI, and 5-FS values for patients undergoing total joint arthroplasty. [Orthopedics. 20XX;XX(X):xx–xx.]



中文翻译:

表型虚弱评分预测老年全关节置换术的围手术期结果

各种评估工具通常用于预测接受全关节置换术的 75 岁以上患者的围手术期发病率。然而,很少有研究描述使用表型衰弱作为结果的预测指标。本研究的目的是使用西奈简略老年评估 (SAGE) 评估表型衰弱,并将其效用与实践中使用的既定评估工具进行比较。我们特别询问:(1) SAGE 能否预测 30 天的结果,包括术后谵妄?(2) SAGE 能否确定延长住院时间的风险?(3) SAGE 是否预测 30 天再入院?(4) SAGE 能否确定排放到专门设施的风险?接受全髋关节置换术和全膝关节置换术的患者使用美国麻醉医师协会身体状况 (ASA)、查尔森合并症指数 (CCI)、5 点改良虚弱评分 (5-FS) 和 SAGE 进行评估。为每位患者确定评估分数,并且分数的每个增量变化用于预测围手术期并发症的可能性。还进行了接受者操作特征分析,以计算每个评估工具的测试灵敏度。SAGE 评分更有可能预测 30 天并发症(比值比 [95 CI],2.21 [1.32–3.70]),与 ASA、CCI 和 5-FS 值相比,术后谵妄 (6.40 [1.78–23.03]) 和住院时间大于 2 天 (3.90 [1.00–15.7])。SAGE 评分不能预测再入院 (1.77 [0.66–4.72]) 或出院至专门机构 (1.48 [0.80–2.75])。与 ASA (0.638)、CCI (0.662) 和 5-FS (0.644) 值相比,SAGE 评分是围手术期发病率更敏感的预测因子(曲线下面积,0.700)。因此,对于接受全关节置换术的患者,SAGE 评分可以可靠地评估围手术期发病率的风险,并且可能比 ASA、CCI 和 5-FS 值具有更好的临床效用。[ 72]) 或排放到专门设施 (1.48 [0.80–2.75])。与 ASA (0.638)、CCI (0.662) 和 5-FS (0.644) 值相比,SAGE 评分是围手术期发病率更敏感的预测因子(曲线下面积,0.700)。因此,对于接受全关节置换术的患者,SAGE 评分可以可靠地评估围手术期发病率的风险,并且可能比 ASA、CCI 和 5-FS 值具有更好的临床效用。[ 72]) 或排放到专门设施 (1.48 [0.80–2.75])。与 ASA (0.638)、CCI (0.662) 和 5-FS (0.644) 值相比,SAGE 评分是围手术期发病率更敏感的预测因子(曲线下面积,0.700)。因此,对于接受全关节置换术的患者,SAGE 评分可以可靠地评估围手术期发病率的风险,并且可能比 ASA、CCI 和 5-FS 值具有更好的临床效用。[骨科。20XX;XX(X):xx–xx.]

更新日期:2022-08-11
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