ABSTRACT

After identifying a captive herd of white-tailed deer in central Texas with >94% seroprevalence with SARS-CoV-2 neutralizing antibodies in September 2021, we worked retrospectively through archived serum samples of 21 deer and detected seroconversion of all animals between December 2020 and January 2021. We then collected prospective samples to conclude that the duration of persistence of neutralizing antibodies is at least 13 months for 19 (90.5%) of the animals, with two animals converting to seronegative after six and eight months. Antibody titres generally waned over this time frame, but three deer had a temporary 4- to 8-fold increases in plaque reduction neutralization test titres over a month after seroconversion; anamnestic response cannot be ruled out.

摘要

在 2021 年 9 月在得克萨斯州中部确定了一群圈养的白尾鹿群，其 SARS-CoV-2 中和抗体的血清阳性率 > 94% 后，我们对 21 只鹿的存档血清样本进行了回顾性研究，并检测了 2020 年 12 月至 2020 年间所有动物的血清转化。 2021 年 1 月。然后，我们收集了前瞻性样本，得出的结论是，19 只（90.5%）动物中和抗体的持续时间至少为 13 个月，其中两只动物在 6 个月和 8 个月后转为血清阴性。抗体滴度在这段时间内普遍下降，但在血清转换后一个月内，三只鹿的斑块减少中和测试滴度暂时增加了 4 至 8 倍；不能排除记忆性反应。