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Checkpoint Inhibitors Can Up Heart Harm
Cancer Discovery ( IF 29.7 ) Pub Date : 2022-08-05 , DOI: 10.1158/2159-8290.cd-nb2022-0051


Patients on ICI therapy rarely experience life-threatening myocarditis, but little is currently known about the risk of other major adverse cardiac events (MACE) in this population. A retrospective study finds that 10% of patients, mostly with advanced cancers, experience MACE, with those with preexisting poor cardiovascular health being at greater risk.

中文翻译:

检查点抑制剂可能会损害心脏

接受 ICI 治疗的患者很少出现危及生命的心肌炎,但目前对该人群发生其他主要不良心脏事件 (MACE) 的风险知之甚少。一项回顾性研究发现,10% 的患者(大多数患有晚期癌症)经历过 MACE,而那些本来就存在心血管健康状况不佳的患者面临的风险更大。
更新日期:2022-08-05
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