Abstract Background Postmastectomy immediate breast reconstruction (PMIBR) may improve the quality of life of patients with breast cancer, of whom older women (aged 65 years or more) are a growing proportion. This study aimed to assess PMIBR in older women with regard to underlying impediments (if any). Methods MEDLINE, Embase, and PubMed were searched by two independent researchers up to June 2022. Eligible studies compared PMIBR rates between younger and older women with invasive primary breast cancer. Results A total of 10 studies (2012–2020) including 466 134 women were appraised, of whom two-thirds (313 298) were younger and one-third (152 836) older. Only 10.0 per cent of older women underwent PMIBR in contrast to 45.0 per cent of younger women. Two studies explored factors affecting uptake of PMIBR in older women; surgeon-associated (usual practice), patient-associated (socioeconomic status, ethnicity, and co-morbidities), and system-associated (insurance status and hospital location) factors were identified. Conclusion Uptake of PMIBR in older women is low with definable (and some correctable) barriers.

中文翻译：

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患有原发性乳腺癌的老年女性立即进行乳房重建：系统评价

摘要 背景乳房切除术后立即乳房重建 (PMIBR) 可以改善乳腺癌患者的生活质量，其中老年女性（65 岁或以上）的比例越来越大。本研究旨在评估老年女性 PMIBR 的潜在障碍（如果有）。 方法两名独立研究人员对 MEDLINE、Embase 和 PubMed 进行了截至 2022 年 6 月的检索。符合条件的研究比较了患有侵袭性原发性乳腺癌的年轻和老年女性的 PMIBR 率。 结果共有 10 项研究（2012 年至 2020 年）接受了评估，涉及 466 134 名女性，其中三分之二（313 298 名）年龄较小，三分之一（152 836 名）年龄较大。只有 10.0% 的老年女性接受了 PMIBR，而年轻女性的这一比例为 45.0%。两项研究探讨了影响老年女性 PMIBR 摄取的因素；确定了与外科医生相关（通常做法）、与患者相关（社会经济地位、种族和合并症）和与系统相关（保险状况和医院地点）的因素。 结论老年女性对 PMIBR 的吸收率较低，存在明显的（以及一些可纠正的）障碍。