In this issue of Cell Host & Microbe, Li et al. unveil an association between HLA-B^∗46:01 and HIV disease progression in Asian populations. The distinct natural killer (NK) cell signature identified in individuals carrying HLA-B^∗46:01 strongly suggests that NK cell inhibition plays a role in loss of HIV control.

中文翻译：

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退缩：HLA 相关的 NK 细胞抑制让 HIV 占得先机

在本期Cell Host & Microbe中，Li 等人。^{揭示 HLA-B *} 46:01 与亚洲人群 HIV 疾病进展之间的关联。^{在携带 HLA-B *} 46:01的个体中发现的独特自然杀伤 (NK) 细胞特征强烈表明 NK 细胞抑制在 HIV 控制丧失中发挥作用。