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Long noncoding RNA H19 alleviates inflammation in osteoarthritis through interactions between TP53, IL-38, and IL-36 receptor.
Bone & Joint Research ( IF 4.7 ) Pub Date : 2022-8-10 , DOI: 10.1302/2046-3758.118.bjr-2021-0188.r1
Yeli Zhou 1 , Jing Li 1 , Feng Xu 2 , Encheng Ji 3 , Chenglong Wang 1 , Zheer Pan 1
Affiliation  

Osteoarthritis (OA) is a common degenerative joint disease characterized by chronic inflammatory articular cartilage degradation. Long noncoding RNAs (lncRNAs) have been previously indicated to play an important role in inflammation-related diseases. Herein, the current study set out to explore the involvement of lncRNA H19 in OA.

中文翻译:

长链非编码 RNA H19 通过 TP53、IL-38 和 IL-36 受体之间的相互作用减轻骨关节炎的炎症。

骨关节炎(OA)是一种常见的退行性关节疾病,其特征是慢性炎症性关节软骨退化。此前已表明长链非编码 RNA (lncRNA) 在炎症相关疾病中发挥重要作用。在此,本研究着手探索 lncRNA H19 在 OA 中的作用。
更新日期:2022-08-10
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