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Unrelated Allogeneic Stem Cell Transplant in Relapsed/Refractory AML: Widening the Yellow Brick Road
Clinical Cancer Research ( IF 11.5 ) Pub Date : 2022-07-25 , DOI: 10.1158/1078-0432.ccr-22-1881
Diego A Adrianzen-Herrera 1 , Aditi Shastri 2
Affiliation  

SummaryA sizable proportion of patients with acute myeloid leukemia (AML) fail to achieve remission. Hematopoietic stem cell transplantation (HSCT) is the only intervention with potential of long-term survival. A recent Acute Leukemia Working Party (ALWP)/European Society for Blood and Marrow Transplantation (EBMT) analysis reports substantial posttransplant survival gains for patients with active disease who received transplants. Decreased relapse was the largest contributor to survival, a cause for optimism in this challenging population.See related article by Nagler et al., p. 4258

中文翻译:

复发/难治性 AML 中的无关同种异体干细胞移植:拓宽黄砖路

摘要相当一部分急性髓系白血病 (AML) 患者未能获得缓解。造血干细胞移植(HSCT)是唯一具有长期生存潜力的干预措施。最近的急性白血病工作组 (ALWP)/欧洲血液和骨髓移植协会 (EBMT) 分析报告显示,接受移植的活动性疾病患者的移植后生存率显着提高。减少复发是生存的最大贡献者,这也是这个充满挑战的人群中乐观的一个原因。参见 Nagler 等人的相关文章,第 17 页。4258
更新日期:2022-07-25
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