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Fine-needle aspiration cytology of juvenile granulosa cell tumour: A case report with summary of prior published cases
Diagnostic Cytopathology ( IF 1.3 ) Pub Date : 2022-08-09 , DOI: 10.1002/dc.25037
Farjana Khatun 1 , Anirban Das 2 , Moumita Sengupta 1 , Uttara Chatterjee 1 , Ruchirendu Sarkar 2
Affiliation  

Juvenile granulosa cell tumours (JGCT) are uncommon tumours of the ovary and can present diagnostic difficulty both on histology and cytology because of its rarity. Here we present the fine-needle aspiration cytology (FNAC) findings of a 4 year-old girl who came with a large abdominal mass and bleeding per vaginum. FNAC from the mass showed features suggestive of granulosa cell tumour (GCT) and which was later confirmed on histology to be of juvenile type. Only two cases of cytological findings of JGCT have been described earlier, both of which were recurrent cases and at metastatic sites. The main cytological feature in our case was presence of thick colloid like fluid containing apparent bubbles along with small clusters of uniform cells with eosinophilic cytoplasm and fine vacuolation. The presence of these secretions corresponding to the macrofollicles on histology has not been reported earlier

中文翻译:

幼年颗粒细胞瘤细针抽吸细胞学检查:一例附已发表病例总结的病例报告

幼年颗粒细胞瘤 (JGCT) 是一种罕见的卵巢肿瘤,由于其罕见,在组织学和细胞学上都存在诊断困难。在这里,我们介绍了一名 4 岁女孩的细针抽吸细胞学 (FNAC) 结果,该女孩患有大的腹部肿块和阴道出血。肿块的 FNAC 显​​示提示颗粒细胞瘤 (GCT) 的特征,后来在组织学上证实为幼年型。之前仅描述了两例 JGCT 的细胞学发现,均为复发病例和转移部位。在我们的病例中,主要的细胞学特征是存在含有明显气泡的厚胶体状液体以及具有嗜酸性细胞质和细小空泡的均匀细胞小簇。
更新日期:2022-08-09
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