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Onset of mental disorders in patients who developed failed back surgery syndrome
European Spine Journal ( IF 2.6 ) Pub Date : 2022-08-09 , DOI: 10.1007/s00586-022-07334-4
Eloise Stanton 1 , Zoe Fresquez 1 , Eric J Muehlbauer 2 , Jeffrey C Wang 1 , Zorica Buser 1, 3, 4
Affiliation  

Purpose

Failed back surgery syndrome (FBSS) is a complex and multifaceted condition associated with significant disability and morbidity. The purpose of this study was to investigate the association between FBSS with new incidences of mental health disorders.

Methods

Our cohort included patients diagnosed with FBSS within 12 months of a posterior fusion, laminectomy, or discectomy, identified using The International Classification of Disease, both Ninth and Tenth Revisions (ICD-9 and ICD-10). In the next step, both non-FBSS and FBSS-diagnosed patients were queried for the diagnosis of first-time occurrence of mental health disorders. The incidence of new mental health disorders was determined within 12-months following FBSS diagnosis.

Results

FBSS patients were significantly at greater risk than non-FBSS patients of developing all included mental health pathologies: Depression: OR 1.9, 95% CI 1.8–2.0, p < 0.0001); Anxiety: OR 1.5, 95% CI 1.4–1.6, p < 0.0001; Sleep Disorder: OR 1.9, 95% CI 1.7–2.0, p < 0.0001; Bipolar Disorder: OR 1.7, 95% CI 1.5–2.0 p < 0.0001; PTSD: OR 1.5, 95% CI 1.3–1.8, p < 0.0001; Panic Disorder: OR 1.8, 95% CI 1.5–2.1, p < 0.0001; Suicidal Disorder: OR 1.7 95% CI 1.4–2.0, p < 0.0001, ADHD: OR 1.3, 95% CI 1.0–1.5, p = 0.0367.

Conclusions

In the current study, patients diagnosed with FBSS were at a significantly greater risk of developing mental health pathologies. While other studies have suggested pre-surgical psychological support and treatment, the current results suggest that a post-operative psychologic care may also be warranted. By identifying potential psychosocial unforeseen obstacles that occur in patients diagnosed with FBSS, more precise treatment pathways can be developed leading to improved patient outcomes.



中文翻译:

背部手术失败综合征患者的精神障碍发作

目的

背部手术失败综合征 (FBSS) 是一种复杂且多方面的疾病,与严重的残疾和发病率相关。本研究的目的是调查 FBSS 与新发精神健康障碍之间的关联。

方法

我们的队列包括在后路融合、椎板切除术或椎间盘切除术后 12 个月内被诊断患有 FBSS 的患者,这些患者使用国际疾病分类第九版和第十版(ICD-9 和 ICD-10)进行识别。在下一步中,非 FBSS 和 FBSS 诊断的患者都被询问是否诊断出首次发生精神健康障碍。在 FBSS 诊断后的 12 个月内确定新的精神健康障碍的发生率。

结果

与非 FBSS 患者相比,FBSS 患者发生所有心理健康病症的风险显着增加:抑郁:OR 1.9,95% CI 1.8–2.0,p  < 0.0001);焦虑:OR 1.5,95% CI 1.4–1.6,p  < 0.0001;睡眠障碍:OR 1.9,95% CI 1.7–2.0,p  < 0.0001;双相情感障碍:OR 1.7,95% CI 1.5–2.0 p  < 0.0001;创伤后应激障碍:OR 1.5,95% CI 1.3–1.8,p  < 0.0001;恐慌症:OR 1.8,95% CI 1.5–2.1,p  < 0.0001;自杀障碍:OR 1.7 95% CI 1.4–2.0,p  < 0.0001,ADHD:OR 1.3,95% CI 1.0–1.5,p  = 0.0367。

结论

在当前的研究中,被诊断患有 FBSS 的患者患精神疾病的风险明显更高。虽然其他研究建议术前心理支持和治疗,但目前的结果表明术后心理护理也可能是必要的。通过识别诊断为 FBSS 的患者中发生的潜在心理社会不可预见的障碍,可以开发更精确的治疗途径,从而改善患者的预后。

更新日期:2022-08-10
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