Objective To develop a reporting guideline for overviews of reviews of healthcare interventions. Design Development of the preferred reporting items for overviews of reviews (PRIOR) statement. Participants Core team (seven individuals) led day-to-day operations, and an expert advisory group (three individuals) provided methodological advice. A panel of 100 experts (authors, editors, readers including members of the public or patients) was invited to participate in a modified Delphi exercise. 11 expert panellists (chosen on the basis of expertise, and representing relevant stakeholder groups) were invited to take part in a virtual face-to-face meeting to reach agreement (≥70%) on final checklist items. 21 authors of recently published overviews were invited to pilot test the checklist. Setting International consensus. Intervention Four stage process established by the EQUATOR Network for developing reporting guidelines in health research: project launch (establish a core team and expert advisory group, register intent), evidence reviews (systematic review of published overviews to describe reporting quality, scoping review of methodological guidance and author reported challenges related to undertaking overviews of reviews), modified Delphi exercise (two online Delphi surveys to reach agreement (≥70%) on relevant reporting items followed by a virtual face-to-face meeting), and development of the reporting guideline. Results From the evidence reviews, we drafted an initial list of 47 potentially relevant reporting items. An international group of 52 experts participated in the first Delphi survey (52% participation rate); agreement was reached for inclusion of 43 (91%) items. 44 experts (85% retention rate) completed the second Delphi survey, which included the four items lacking agreement from the first survey and five new items based on respondent comments. During the second round, agreement was not reached for the inclusion or exclusion of the nine remaining items. 19 individuals (6 core team and 3 expert advisory group members, and 10 expert panellists) attended the virtual face-to-face meeting. Among the nine items discussed, high agreement was reached for the inclusion of three and exclusion of six. Six authors participated in pilot testing, resulting in minor wording changes. The final checklist includes 27 main items (with 19 sub-items) across all stages of an overview of reviews. Conclusions PRIOR fills an important gap in reporting guidance for overviews of reviews of healthcare interventions. The checklist, along with rationale and example for each item, provides guidance for authors that will facilitate complete and transparent reporting. This will allow readers to assess the methods used in overviews of reviews of healthcare interventions and understand the trustworthiness and applicability of their findings. All data are presented in the manuscript and supplemental files.

中文翻译：

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医疗干预审查概述报告指南：PRIOR 声明的制定

目的 制定医疗干预审查概述的报告指南。为审查概述 (PRIOR) 声明设计开发首选报告项目。参与者 核心团队（七人）领导日常运营，专家咨询小组（三人）提供方法建议。一个由 100 名专家（作者、编辑、读者，包括公众成员或患者）组成的小组应邀参加了经过修改的 Delphi 练习。11 名专家小组成员（根据专业知识选出，并代表相关利益相关者群体）被邀请参加虚拟面对面会议，以就最终清单项目达成一致（≥70%）。最近发表的综述的 21 位作者受邀对该清单进行了试点测试。设定国际共识。干预 EQUATOR Network 为制定健康研究报告指南建立的四个阶段流程：项目启动（建立核心团队和专家咨询小组，注册意向），证据审查（对已发表的概述进行系统审查以描述报告质量，方法学范围审查指南和作者报告了与进行审查概述相关的挑战），改进的 Delphi 练习（两次在线 Delphi 调查以就相关报告项目达成一致（≥70％），然后进行虚拟面对面会议），以及报告的开发准则。结果 根据证据审查，我们起草了一份包含 47 个潜在相关报告项目的初始清单。一个由 52 名专家组成的国际小组参加了第一次德尔福调查（52% 的参与率）；就纳入 43 个 (91%) 项目达成了一致意见。44 名专家（保留率 85%）完成了第二次德尔福调查，其中包括第一次调查中不一致的四个项目和根据受访者评论新增的五个项目。在第二轮中，没有就包含或排除其余九个项目达成协议。19 人（6 名核心团队和 3 名专家顾问组成员，以及 10 名专家小组成员）参加了虚拟面对面会议。在所讨论的九个项目中，高度一致的是三个被纳入，六个被排除。六位作者参与了试点测试，对措辞进行了细微改动。最终清单包括 27 个主要项目（19 个子项目），涵盖审查概览的所有阶段。结论 PRIOR 填补了医疗干预审查概述报告指南中的一个重要空白。该清单连同每个项目的基本原理和示例，为作者提供了指导，以促进完整和透明的报告。这将使读者能够评估在医疗干预审查概述中使用的方法，并了解他们的发现的可信度和适用性。所有数据都显示在手稿和补充文件中。这将使读者能够评估在医疗干预审查概述中使用的方法，并了解他们的发现的可信度和适用性。所有数据都显示在手稿和补充文件中。这将使读者能够评估在医疗干预审查概述中使用的方法，并了解他们的发现的可信度和适用性。所有数据都显示在手稿和补充文件中。