Every year more and more innovative pharmacological agents are introduced medicine, to treat systemic diseases. Due to these rapid and recent advancements, many patients are receiving treatment with a high variety of drugs, such as selective serotonin reuptake inhibitors, bisphosphonates, tumor necrosis factor (TNF)-α inhibitors, cyclosporine, and steroids. Since implant and osseous surgery are common treatment modalities used, within dentistry, it is of critical important to acknowledge and discuss the potential effects of selective serotonin reuptake inhibitors, bisphosphonates, TNF-α inhibitors, cyclosporine, and steroids, on bone healing. The present paper discusses the possible detrimental ramifications and risks these drug classes may have on bone healing.

中文翻译：

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药物相关的骨吸收与潜在的牙科和种植体影响

每年都有越来越多的创新药物被引入医学，以治疗全身性疾病。由于这些快速和近期的进展，许多患者正在接受多种药物的治疗，例如选择性血清素再摄取抑制剂、双膦酸盐、肿瘤坏死因子 (TNF)-α 抑制剂、环孢菌素和类固醇。由于种植体和骨手术是牙科中常用的治疗方式，因此了解和讨论选择性血清素再摄取抑制剂、双膦酸盐、TNF-α 抑制剂、环孢素和类固醇对骨愈合的潜在影响至关重要。本文讨论了这些药物类别可能对骨愈合产生的不利影响和风险。