Nutrition plays a critical role in the homeostatic balance, maintenance of health, and longevity. There is a close link between inflammatory diseases and nutritional health. Obesity is a severe pathological process with grave implications on several organ systems and disease processes, including type 2 diabetes, cardiovascular disease, osteoarthritis, and rheumatoid arthritis. The impact of obesity on periodontal inflammation has not been fully understood; the association between nutritional balance and periodontal inflammation is much less explored. This review is focused on the potential mechanistic links between periodontal diseases and obesity and common inflammatory activity pathways that can be pharmacologically targeted.

中文翻译：

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炎症是牙周病和肥胖之间的联系

营养在体内平衡、维持健康和长寿方面起着至关重要的作用。炎症性疾病与营养健康之间有着密切的联系。肥胖是一种严重的病理过程，对多个器官系统和疾病过程具有严重影响，包括 2 型糖尿病、心血管疾病、骨关节炎和类风湿性关节炎。肥胖对牙周炎症的影响尚未完全清楚；营养平衡与牙周炎症之间的关系鲜为人知。这篇综述的重点是牙周病和肥胖之间的潜在机制联系，以及可以药理学靶向的常见炎症活动途径。